Match the column on the left to the descriptions on the right
that apply to it. There can be more than one answer to each item.
All proteins are from E. coli.
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2-3 copies occur in the functional unit Has 6 identical subunits Requires ATP Binds to the replication helicase Binds specific sequences of double-strand DNA Has 3′ exonuclease activity Has 5′ exonuclease activity E. Clamp (B subunit) F. τ protein G. DnaA H. Replication Helicase (DnaB) 1. Clamp loader (γ complex) . Topoisomerase I K. DNA gyrase L. DNA ligase M. Dam methylase Requires all 4 types of ribonucleotide triphosphates Component of DNA polymerase III holoenzyme Makes and seals single-strand breaks in DNA Binds to the clamp loader Binds non-specific sequences of single-strand DNA Requires deoxyribonucleotide triphosphates Drives the movement of the replication fork Interacts with the clamp Introduces negative supercoils Closes single-strand breaks in DNA Opens the duplex DNA at the origin of replication
