A potential food additive was given to rats (approximately 1 lb
weight) to test its efficacy. Dosages were increased until effects
were noted, including fatalities. The data follows:
100% Original paper Customized to your instructions!
What are the ED50 and LD50 (Hint
plot the data)
What is your recommendation as to the limit placed on human
(assume 150 lb weight) exposure? Explain your reasoning. Note: This
is ingestion so use weight vs. lung volume as the scaling
factor
Dose #Rats Number Number mg Tested Affected Fatalities 15 30 45 60 90 100 150 170 200 250 300 500 25 25 25 24 24 26 25 20 25 28 28 7 16 14 13 21 19 24 26 26 4 4 10 16 12 19