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Question: A potential food additive was given to rats (approximately 1 lb weight) to test its efficacy. Dos…

by | Aug 27, 2021 | Questions & Answers

A potential food additive was given to rats (approximately 1 lb
weight) to test its efficacy. Dosages were increased until effects
were noted, including fatalities. The data follows:

Question: A potential food additive was given to rats (approximately 1 lbweight) to test its efficacy. Dos...   

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What are the ED50 and LD50 (Hint
plot the data)

What is your recommendation as to the limit placed on human
(assume 150 lb weight) exposure? Explain your reasoning. Note: This
is ingestion so use weight vs. lung volume as the scaling
factor

Dose #Rats Number Number mg Tested Affected Fatalities 15 30 45 60 90 100 150 170 200 250 300 500 25 25 25 24 24 26 25 20 25 28 28 7 16 14 13 21 19 24 26 26 4 4 10 16 12 19

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